ZOO 3000 Lecture Notes - Lecture 18: Zipper, Renal Pelvis, Macula Densa

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Functions: urine production removes wastes, while conserving fluids and electrolytes, maintain acid-base balance, regulates extracellular fluid, endocrine activities secretion of epo and renin, hydroxylation of vitamin d precursor. Separated into regions hilum, capsule, cortex and medulla. Lobes are defined by medullary pyramids or renal columns and their associated cortical tissue: medullary pyramid ends in renal papilla, papilla projects into minor calyx renal pelvis ureter. Nephron: nephrons are the structural and functional unit of the kidney . 2x106/kidney: nephron consists of 2 portions, renal corpuscle functions in the ultrafiltration of blood to produce primary urine (1, tubule system functions in the conducting and processing of primary urine (2-9) Function container: visceral layer, complex filtration barrier. Function ultrafiltration: between the layers urinary space, the receptacle of the ultrafiltrate (primary urine, the visceral layer of the renal corpuscle forms a triple barrier. Size-selective physical barrier for compounds less than 70kda.

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