BGEN 3020 Lecture Notes - Lecture 24: Personal Genome Project, Tumor Suppressor Gene, Genetic Testing
21 Mar 2019
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Document Summary
Genetic non-discrimination act: bill s-201 (gna) was passed in may 2017, it prevents companies from compelling genetic testing or the disclosure of genetic testing results. Example: huntington"s: children of a parent with huntington"s can be tested, many choose not to be, an insurance company would like this information, gna means they cannot compel testing. Insurance pov: before 2017, insurance companies were asking for prior results if the policy was over k, they were not compelling genetic testing, voluntary policies of the industry. Quebec challenge: province of quebec has challenged the act on constitutional grounds, insurance is a provincial responsibility, so the federal gov cannot pass this act, currently before the courts. Would it be useful to sequence everyone: cost, ethics benefits. Pharmacodynamics: malignant hyperthermia: life-threatening fever, muscle contraction in response to inhaled anesthetics, allergic and non-allergic immune reactions. Genetic sex determination systems: heteromorphic: structurally different sex chromosomes, like human x and y chromosomes.
