BGEN 3020 Lecture Notes - Lecture 9: Heme A, Thrombin, Heparin

• School: University of Manitoba
• Department: Biochem. and Medical Genetics
• Course: BGEN 3020
• Professor: Jason Leboe- Mcgowan

Document Summary

In coagulation deficiency, you different sign"s symptoms, such as: delayed bleeding ie go through operation with no prob, then the pt starts moving around that"s when it"s bad. When pt has an operation and they start bleeding out of the wound, the mcc is not a coagulation factor deficiency; the. Mcc is due to suture slipped or a bleed. When you have a coag deficiency, just have to tie it off. Example: molar extraction with constant oozing of blood b/c nothing holding those small vessels together except a temp hemostatic plug need a tight fibrin bond to plug it up. Example: it is showing hemorrhage into the fascial compartment of the thigh. In the knee, there are repeated hemarthroses and the pt has hemophilia a. Will not see hemarthroses or bleeding into spaces with platelet abnormalities, but only coagulation factor deficiency. However, they also have a factor 8 deficiency, but it is very mild and never severe.