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Lecture 26

BIOL 1000 Lecture 26: Biology Lecture 26

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Biological Sciences
BIOL 1000
Kevin G.Scott

Biology Lecture 26: Mendelian Inheritance in Bhvr of chromosomes Chromosome theory of inheritance states: 1. Mendelian genes have specific loci on chromosomes 2. Chromosomes undergo segregation and independent assortment Morgan and Other Stuff Behavior of chromosomes during meiosis was said to account for Mendels law of segregation and independent assortment. First solid evidence associating a specific gene with a specific chromosomes came from Thomas Hunt Morgan, an embryologist Morgans experiments with fruit flies provided convincing evidence that chromosomes are the location of Mendels heritable factors Several characteristics make fruit flies suitable for genetic studies They breed at a high rate A generation can be bred every two weeks They have only 4 pairs of chromosomes *Morgan noted wild type, or normal phenotypes that were common in the fly populations Traits alternative to the wild type are called mutant type In one experiment Morgan mated male flies with white eyes(mutant) with female flies with red eyes (wild type) F1 generation all had red eyes F2 generation showed the 3:1 red: white ratio, but only, males had white eyes. Half of males had red, half of males had white eyes. Genes that Thomas found were found on sex chromosomes Y chromosome didnt have color for eye gene Sex Linked Traits: In humans and some other animals there is a chromosomal basis of sex determination In humans and other mammals there are two varieties of sex chromosomes a larger X chromosome and a smaller y chromosome Only ends of y chromosome have regions that are homologous with the x chromosome The SRY gene on the Y chromosome codes for the development of testes Females are XX and males are XY Each ovum contains an X chromosome while a sperm may contain either an X or a Y chromosome
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