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BIOL1412 03 24 2014.docx

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Department
Biological Sciences
Course
BIOL 1412
Professor
Paul Messing
Semester
Winter

Description
BIOL1412 03 24 2014  Recall: blood is buffered ∴ takes large change in H+ to change pH  PO 2 ­ stimulus receptors when P2 reaches ­ 50­60  mmHg  (Fig. 22.20) (end of plateau of H2 curve)  emergency situation   PO 2 ⇓ due to lung disease low atm P2 ii. central chemoreceptors ­ medulla oblongata (dominant control)  responds indirectly to arterial 2 (Fig. 22.24)  resting arterial PC = 40 mmHg (set point = 37­43)  in CSF: CO 2     +   2O                        3          H+     +   3­HCO                                                    carbonic anhydrase                    detect  CSF poorly buffered ⇒ small change stimulate response d. other factors Factor Effect of Ventilation 1. ⇑ temperature ⇑ ventilation 2. ⇓ temperature ⇓ ventilation 3. ⇑ emotion ⇑ ventilation 4. ⇑ proprioceptor discharge (exercise before change in      ⇑ ventilation    blood gases occurs) 5. sudden ⇑ bp ⇑ ventilation 6. sudden ⇓ bp ⇓ ventilation 7. Pain ­ sudden stops ventilation 8. Pain ­ chronic ⇑ ventilation 9. Cold ­ sudden stops temporarily 10. stretch anal sphincter (Not on Exam!) ⇑ ventilation Clinical Application 1) Hyperventilation  ⇓ arterial PCO2 ⇒ cerebral vasoconstriction (intrinsic metabolic response) ∴ 2 to brain ⇒ dizziness 2) Hypoventilation  ⇑ arterial PCO2, ⇑ H+ = acidosis 3) CO poisoning  CO ­ incomplete burning of gas (cars, furnaces)  CO binds 210x more strongly to Fe than 2 = carboxyHb (HbCO)  result: total ⇓2O  no change in PO2 or PCO 2 (dissolved gases)  ∴ ventilation rate doesn't change Final EXAM!  April 15th @ 1:30 pm  70 Questions  10 questions from lab 4 + 5  15 on 1st half Topic X: Digestive System Physiology Digestion  involves: 1) Digestive Tract ­ mouth to anus (Fig. 23.1) 2) Accessory Organs ­ eg. teeth, salivary glands, liver, pancreas, etc.  Four Basic Processes: 1) Digestion ­ breakdown of large food pieces into small molecules
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