BIOL 1020 Lecture Notes - Lecture 19: Chromatin, Prometaphase, Nuclear Membrane

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BIOL 1020 Full Course Notes
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Mitosis is conventionally divided into five phases: prophase, prometphace, metaphase, anaphase, telophase. Prophase: chromosome consisting of two sister chromatids, mitotic spindle begins to form. Prometaphase: fragments of nuclear envelope, nuclear envelope disappears and chromosomes flow in cytoplasm and begin to line up. Metaphase: lining up along the metaphase plate. Anaphase: ripping apart of the chromosomes, then there are two single stranded chromosomes that go to opposite ends of the cell. Telophase and cytokinesis: nuclear envelope forming, nucleolus forming, cleavage furrow. The mitotic spindle is an apparatus of microtubules that control chromosomes movement during mitosis. During prometapahase, assembly of spindle microtubules begin in the centrosome, the microtubules organizing center. The centrosome replicates, forming two centrosomes that migrate to the opposite ends of the cell, as spindle microtubules grow out of them. An aster (a radial array of short microtubules) extends from each centrosome. The spindle includes the centrosomes, the spindle microtubules, and the asters.

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