BIOL 1020 Lecture Notes - Lecture 12: Allosteric Regulation, Metabolic Pathway, Isoleucine

• School: University of Manitoba
• Department: Biological Sciences
• Course: BIOL 1020
• Professor: Joy E.Stacey

Document Summary

Biol 1020 lecture 12: feedback inhibition, thermodynamics of metabolism and the electron carrier (oxidation/reduction) If cell using product does not bind, and process continues: do not have to remember this case but the general pathway. Metabolism governed by thermodynamics: matter and energy are conserved, energy/matter cannot be created or destroyed, there is always an increase in disorder; entropy always increases. Living things do not violate laws of thermodynamics: cells create ordered structures from less ordered materials create disorder elsewhere, matter/energy conserved. Energy profiles of chemical reactions: free energy changes, delta g = (free energy final) (free energy initial, = (free energy products) (free energy reactants) Case 1: higher initial free energy: products have a lower free energy, energy released, negative delta g, example: If final = 5, initial = 10: delta g = -5, exogenic, energy lost from molecules, such as hydrolysis of atp. Case 2: higher final free energy: products have a higher free energy.