BIOL 1020 Lecture Notes - Lecture 32: Dna Replication, Archaea, Eukaryote

• School: University of Manitoba
• Department: Biological Sciences
• Course: BIOL 1020
• Professor: Joy E.Stacey

Document Summary

Completing and targeting the functional protein: often translation is not suf cient to make a functional protein, polypeptide chains are modi ed after translation, completed proteins are targeted to speci c sites in the cell. Proteins folding and post-translational modi cations: during and after synthesis, a polypeptide chain spontaneously coils and folds into its three-dimensional shape, proteins may also require posy-translational modi cations before doing their job. Targeting polypeptides to speci c locations: two populations of ribosomes are evident in the cells: free ribosomes (in the cytosol) and bound ribosomes (attached to the er), free ribosomes mostly synthesize proteins that function in the cytosol. Types of point mutations: point mutations within a gene can be divided into two general categories. Zubaida al-khashab: nonsense mutations change an amino acid codon into a stop codon, nearly always leading to a nonfunctional protein.