BIOL 2420 Lecture Notes - Lecture 16: Common Bile Duct, Ulcerative Colitis, Gallstone

• School: University of Manitoba
• Department: Biological Sciences
• Course: BIOL 2420
• Professor: Diana Mlinar

Document Summary

Erosion of gastric, esophageal or duodenal surface. Occurs due to breakdown of mucosal barrier by acid and pepsin. Helicobacter pylori implicated in >80% of all peptic ulcers. Produces urease - makes a base and neutralizes the stomach acid. Use the mucus and glycoproteins for food. The a(cid:272)id does(cid:374)"t da(cid:373)age the wall of the sto(cid:373)a(cid:272)h. Can involve any of all secretions of the digestive tract. Onset most frequently in early adult life. Can affect any portion of the digestive tract. Most common in the ileum and ascending colon. Patches of ulceration interspersed with healthy tissue. Ulcerations can penetrate through entire layer of bowel wall. Holes in the wall of the gi tract. Causes inflammation and ulceration of the inner lining of the colon and rectum. Constipation with passage of blood or mucus in the stools. Colectomy (surgery removal of colon) eliminates illness. Hypersensitivity response of intestinal mucosa to gluten. Result: destruction of the villus of epithelial cells.