BIOL 2420 Lecture Notes - Lecture 24: Myenteric Plexus, Voltage-Dependent Calcium Channel, Submucous Plexus

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Questions at the beginning of class: list the general organizations of the gi tract (muscle layers, look at three exceptions to the general organization. Oblique layer in the stomach (4 layers) Skeletal muscle in the upper esophagus (also smooth muscle there) To keep the cells polarized, we have a different set of proteins on the blood and lumen side. Must be transported through the cells (except for water) The gi tract is controlled locally by the enteric nervous system (ens) Runs from the esophagus to the anus. Between the circular and longitudinal muscle layers. Resting membrane potential of muscle cells (vr = -50 mv) Slow waves at rest are triggered by intestinal cells of cajal (icc) Electrical slow waves (+ action potentials) spread from icc to smooth muscle cells. Changes of membrane potential vm are spreading form muscle cell to muscle cell via gap junctions.

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