BIOL 2500 Lecture Notes - Lecture 19: Stabilizing Selection, Coronary Artery Disease, Haplotype

• School: University of Manitoba
• Department: Biological Sciences
• Course: BIOL 2500
• Professor: Roman Gietz

Document Summary

Heritability measures the genetic component of phenotypic variation. The concept of heritability was developed to help measure the proportion of phenotypic variation that is due to genetic variation. Heritability differs from trait to trait o. The phenotypic variation of a trait with high heritability is largely the result of genetic variation, whereas only a small proportion of phenotypic variation of a trait with low heritability can be attributed to genetic variation. Heritability is an important measure of the potential responsiveness of a trait to selection. Broad sense heritability (h2) estimates the proportion of phenotypic variation that is due to total genetic variation: h2 = vg/vp. Narrow sense heritability (h2) estimates the proportion of phenotypic variation that is due to additive genetic variation o h2 = va/vp. Both are expressed as proportions ranging in magnitude from 0 to 1. Four attributes of heritability are central to its meaning o.