ACB 330 Lecture Notes - Lecture 6: Zygote, Acrosome Reaction, Tunicate
Document Summary
Resact 14 amino acid peptide used by sea urchins. Difuses from eggs binds to receptor on pm of sperm. Arcosome reaction when spermatozoan interact with polysaccharides in the jelly coat. Increases opening ca2+ channels in sperm membranes a acrosome membrane fuses with sperm pm. Enzyme released digests path through jelly. b activated rho gtpase globular actins polymerizes acrosomal process is extended. Bindins located on inner surface of sperm acrosome reaction bindins now on outside bindins adhere to egg receptors. (highly species specific). Oviduct fluid leads sperm to increase opening of ca2+ channels in sperm tail. + albumin removes cholesterol from sperm pm (increases fluidity of sperm pm, increases ability to fuse acrosomal) + unmasking of zona pellucida proteins in sperm head. Thermotaxis: temperature gradient ~2c between entrance to oviduct and ampulla. Acrosome reaction: triggered when enters cumulus cell layer. Relocates izumo protein to the outer surface. (cid:862)hyaluro(cid:374)idase(cid:863) enzyme that allow sperm to digest path through cumulus layer.