BIOL303 Lecture Notes - Lecture 4: Zona Pellucida, Vitelline Membrane, Acrosome Reaction

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Acrosome modified secretory vesicle, derived from the golgi apparatus, in front of the nucleus that contains enzymes and complex sugars used to get through the outer membranes of the egg. Capacitation final process of maturation that mammalian sperm go through, in the oviduct of the female reproductive tract, that is essential for fertilization of the ovum. Egg/ovum female gamete capable of binding sperm and being fertilized. Oocyte a developing egg that cannot yet bind sperm or be fertilized. Dictyotene the resting phase of the oocyte in mammals. Vitelline membrane thin, tough layer of extracellular matrix in invertebrates. Zona pelucida thick matrix in the extracellular envelope in mammals. Cumulus a layer of ovarian follicle cells that surround the egg and nurture it at time of release from ovary. Cortical granules membrane bound and golgi-derived molecules that contain digestive enzymes, mucopolysaccharides, adhesive glycoproteins and hyaline glycoproteins. Pip2 secondary messenger system pip2 is cleaved by plc to make ip3 and dag.

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