NUTR 120 Lecture 13: 31-01-2017
Document Summary
Nutr 120 31-01-2017 oxidation, free radicals & antioxidants. In lipoproteins ldl--(antioxidant) r* oxldl: connection to cancer, stages of cancer. 1 initiation (dna damage) causes: free radicals may try to abstract a dna, viruses, pah (polycyclic compounds; poly aromatic hydrocarbons). It depends on how frequent we are exposed to these to reduce the risks, uv rays. This will lead to apoptosis (kills itself), repair; which require nutrients: promotion (benign) causes: malondiadehyde breakdown products of oxidized fats, progression: diffuse type of growth & develop its own circulatory system, metastasis (spread) We (cid:272)a(cid:374)"t preve(cid:374)t (cid:271)ut redu(cid:272)e the risk or (cid:373)itigate dseases. R damage: a) dna (initiation: pufa in, body cell membranes, ldl, proteins: cataracts (due to r*- mediated oxidation of the protein in the lens of the eye) Key points: present in only animal (present in all the foods animal cells, body makes all cholesterol in need! (cholesterol not an essential nutrient).
