PHSI 208 Lecture Notes - Lecture 3: Peritubular Capillaries, Renal Blood Flow, Afferent Arterioles
Document Summary
Renal blood flow (rbf) alterations in afferent and efferent resistances: But, blood is entering the glomerulus at the same rate as control. It"s not just leaving as readily, therefore ph increases and. Site of resistance is found at the end of the circuit. More blood is entering the glomerulus but it is leaving at the same rate, therefore ph increases and gfr increases. But, blood is flowing into the glomerulus at the same rate, but now more readily leaves. This means less pooling and a decrease in hydrostatic pressure. Primarily afferent control via myogenic autoregulation and tubuloglomerular feedback. Larger increase in overall resistance results in larger decrease in rbf. Decreased ph, decreased rbf, decreased hydrostatic pressure, decreased glomelular filtration rate. Renal threshold is the plasma concentration of a solute when it first begins to appear in the urine at the point of transport maximum. Basically, if it is above the renal threshold, its in your urine!
