BIOL130 Lecture Notes - Lecture 9: Sister Chromatids, Spindle Apparatus, Nuclear Membrane

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Unit 9: mitosis, meiosis, cell cycle - november 10, 15, 17. What signals should the cell be to for division. What happens if the signal is ignored. How the brake mechanisms work when there is uncontrolled division. Multicellular (metazoans): many cells divide to create one being. Need to replicate dna and separate into different cells. Mitosis: cells are cloning themselves, creating genetically identical cells. Meiosis: doubling and splitting twice, cells are not genetically identical, creates variety. Two copies of each essential to survival. Only short, fuzzy and compacted for a little while. Based on the short, fuzzy, highly condensed versions of chromosomes. Trick the cells into going through the division cycle and stop them when they are at that point. A spindle toxin is introduced that breaks down the spindle fibers, and then break cells open and arrange the chromosomes in order. Homologues: a pair of chromosomes, one from each parent.

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