BIOL239 Lecture Notes - Lecture 8: Rna Splicing, Primary Transcript, Alternative Splicing
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17 Apr 2016
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Transcription: the process by which the polymerization of rib-nucleotides guided by complementary base pairing produces an rna transcript of a gene. Rna polymerase: the enzyme that catalyzes transcription. Promoters: dna sequences near the beginnings of genes that signal rna polymerase where to begin transcription. Terminators: sequences in the rna products that tell the rna polymerase where to stop (encoded by dna) Polyribosome: a complex of several ribosomes translating from the same mrna. Nucleotides are added in a 5"-3" direction. Uracil is in place of thymine in rna. Rna polymerase binds to the double-stranded dna at the beginning of the gene to be copied. Rna polymerase recognizes and binds to the promoter region- particular sequence (in the gene (dna) but not the mrna), Brings in the holo-enyzme, the core polymerase that does the polymerization of the rna molecule. The complex formed between the rna polymerase holoenzyme and unwound promoter region is called the open promoter complex.
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