BIOL239 Lecture Notes - Lecture 8: Chromosome

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Recombination frequencies can represent a distance map distance between genes. If two genes are linked they are def on the same chromosome If they aren"t linked doesn"t mean they have to be on diff chromosomes. Strutavan - took two genes, two crosses each time. Y and r, very far apart from one another, add all the genes in between (55) Don"t have to do all the breeding experiments to get all the distances, take flies that are mutant for these genes and get all the correct distances. Error occurs because missing parts of recombination. Tracking recombination events tracking crossover events, if you miss crossover events it will mess your numbers up. Ignoring pr will give you an inaccurate distance. Finding the order of gene linkage and map distances using 3 point crosses: Phenotypes in the f2 tell us the cross overs that occur. In this case it"s 2 to the power of 3 should have 8 sets.

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