BIOL240 Lecture Notes - Lecture 6: Holliday Junction, Repressor Lexa, Histidine
Document Summary
Microbiology notes: week 6: genetics and molecular biology. Introduction to terminology of molecular biology: mutant: strain carrying a mutation. Mutation and mutant aren"t the same thing: mutation: change that occurs within the gene that makes another allele of the gene or disrupt the function of the gene. Can have gain of function, loss of function, change of function. All occurring at the dna level: genotype: description of all of the alleles within an organism. Genotype is the allele in a strain related to the wild-type of the organism, The would indicated that its disrupted in its function: phenotype: observable properties of the strain that contains the mutation. The will not be able to creates its own: wild-type: the strain found in nature, The original isolate of a strain that all mutants are derived from. The phenotypes of mutations: selection versus screening: selectable: Phenotypes of mutation can often be selectable:
