BIOL302 Lecture Notes - Lecture 4: Chondrocyte, Multinucleate, Epiphyseal Plate

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9 Apr 2018
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Function: support and attachment of muscle, protection of soft organs, storage and mobilization of calcium, marrow (blood cells) Function: synthesize bone and secrete osteoid: osteoid = demineralized matrix located outside the bone, periosteum (under ct, endosteum inactive = squamous, active = cuboidal, ultrastructure, rer, golgi, vesicles. Function: resorption of bone: secrete enzymes and acid, endocytosis - vesicles, blood vessels, multinucleated and larger, ruffled border = absorption, clear zone = adhesion, often seen lying in depressions resorbed from bone surface called howship"s la(cid:272)unae. Osteocytes: located inside the bone, surrounded by matrix, lacunae, canaliculi, gap junctions. Periosteum: exterior surface of bone, outer fibrous layer, dense irregular ct, blood vessels/ nerves. Inner fibrous layer: osteogenic layer, looser ct, cuboidal cells (active osteoblasts, continuity with collagen of bone, sharpey"s fi(cid:271)ers. Interior surface bone: lines marrow cavity, simple squamous, cuboidal when active. Primary bone: woven bone (immature, collagen arrays are random, low mineral content, lots of osteocytes.

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