BIOL303 Lecture Notes - Lecture 7: Morphogen, Syncytium, Sea Urchin
Document Summary
Below certain level of hunchback will not get any expression. Bicoid kruppel was expanded which only has the hunchback therefore no proper. Leads to segmentation of the body-7 transverse genes. Primary- coming on and interperate gap gene patterns- expression associated with a different enhancer-gap gene combination. Used products of primary to turn on expressions. Do not all overlap- each region will be alittle different. Made constructs that express lac z- don"t work very strongly until enhancer works with it. Pair rules- do not coincide causing more diversity and difference in each segment. All gap and pair rule encode transcription but moving from syncytial to blastoderm but you will also see cell/cell signaling machinery. Activate engrailed by ftz and eve, and supresses wingless. Must be a second signaals- looked at lethal mutant phenotypes. Hh expressed in en and lost in wnt- hh is gene responsible for the signal to maintain parassegments.
