BIOL303 Lecture Notes - Lecture 1: Germ Layer, Alternative Splicing, Developmental Biology

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No actin microfilaments, no microtubules: most prokaryotic genes: Produce polycistronic mrna one transcript can code for many different peptide products. Eukaryotes: can be unicellular or multicellular, genetic material is enclosed within membrane-bound nucleus, membrane-bound organelles, size: 10-100 m in diameter (some protists can be up to 500 m, ribosomes 80s (60s+40s) Histones are proteins embedded in the dna. Nucleosomes are the basic functional unit of chromatin which consists of 8 histone proteins and. Chromatin is the resulting dna that makes up the chromosomes (thread that is wound up and coiled: sexual reproduction through meiosis, cytoskeletal elements (actin microfilaments and microtubules, most eukaryotic genes: Contains introns for splicing out (yeast is an exception); alternative splicing genes give us different isoforms of proteins. T(cid:396)a(cid:374)s(cid:272)(cid:396)ipts (cid:271)i(cid:374)d (cid:396)i(cid:271)oso(cid:373)e (cid:271)y (cid:373)ea(cid:374)s of (cid:1009)" (cid:373)rna (cid:272)ap. This is so that they can divide into haploid cells. Actual crossing over and subsequent genetic recombination is a byproduct of how tightly packed they are.

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