BIOL308 Lecture Notes - Lecture 12: Ribonucleoprotein, Dna Replication, Ribozyme
16 Jul 2014
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Lagging strand: when the final rna fragment is removed from the 5" end of the lagging strand, there is no upstream strand [ no available 3"oh] onto which dna pol i can build to fill the gap. Chromosomes loose about 100 base pairs from their 5" ends in each mitosis. Telomere: the natural end of a linear chromosome. Dna sequence consists of a simple repeating unit [6-7 nt] with a protruded single-stranded 3" end that may fold into a loop. Telomerase: enzyme that repairs, replicates the ends of chromosomes. Summary: telomerase is a ribonucleoprotein, protein that has rna, polypeptide part and rna part, a ribozyme, the rna performs the action, in a protein, the protein carries out action. Unicellular eu organisms, cells that proliferate indefinitely as they have to reproduce. Possess homeostatic mechanisms to maintain telomere length within a limited range. Somatic cells are born with full complement of telomeric repeats.
