BIOL308 Lecture Notes - Lecture 20: Current Biology, Pearson Education, Poly(A)-Binding Protein
4 Feb 2015
School
Department
Course
Professor
Document Summary
What is catalytically active component of snrnp: pre-mrna are spliced by same reactions that occur in self-splicing group ii introns. The snrnas required for splicing are very similar to parts of the self- splicing group ii introns; combined snrnas (u6 and u2) have similar structure (conformation) to the structure of self-splicing group ii introns. Snrna are catalytically active components of snrnps (ribozyme) Proteins probably have supplementary role: sites of interaction with regulatory factors, maintaining of proper 3d structure, transport (similar to the role of maturases) . Rna processing and post- transcriptional / pre-translational control. Learning objectives: alternative splicing and trans-splicing, describe role of transport through nuclear pore in, describe different mechanisms of post-transcriptional/ control of gene expression pre-translational control of gene expression. Eukaryotes can have simple and complex transcription units: simple transcription units. Eukaryotes can have simple and complex transcription units.
