BIOL308 Lecture 3: Lecture 3

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1868 - the swiss biologist, friedrich miescher, isolated dna from salmon sperm. 1944 - oswald avery, colin macleod, and maclyn mccarty showed that pathogen characteristic is transferred from pathogenic strains of the bacterium. Pneumococcus to nonpathogenic strains through transfer of dna. 1947 - erwin chargaff reported that the quantities of a&t and g&c in dna were very close to the same value. 1952 - alfred hershey and martha chase showed t2 bacteriophage injects only. Dna into cells and this is sufficient to make more t2 bacteriophage. 1953 - james watson and francis crick proposed the model of the double helix of dna. 1958 - matthew meselson and fanklin stahl demonstrated that dna replication occurred by a semi-conservative mechanism in which a parental duplex is replicated into two identical daughter duplexes. 1965 - marshall nirenburg, philip leder, and others, identified the genetic code by which protein is made from information in dna.

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