BIOL370 Lecture Notes - Lecture 7: Renal Function, Calcium Atpase, Afferent Arterioles
24 Dec 2012
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Document Summary
Transporter expression in epithelial cells controls solute uptake & deposition. Length of the loop is directly related to urine concentration. Countercurrent multiplication is a key to producing concentrated urine. Internal organ with multiple cell types tubule that maintains ion & water balance. Ion balance: na: osmotic balance: urine volume, blood pressure: long term regulator, ph balance: w/ respiratory system [h+ vs. hco3, excretion of metabolic wastes & toxins, hormone production: renin that controls bp & erythropoietin that regulates rbc synthesis. Mammalian kidney (filtration reabsorption secretion excretion: outer cortex + inner medulla, kidney ureter urinary bladder urethra, functional unit of the kidney: nephron. Renal tubule: 1 layer of transport epithelium with specific transport functions @ different segments. Associated vasculature blood vessels : glomerulus surrounded by bowman"s capsule & capillary beds that surrounds the renal tubule: cortical nephrons: loop of henle is located predominately @ outer cortex. Peritubular capillaries are efferent arterioles that drains the cortical nephrons.
