BIOL373 Lecture Notes - Lecture 6: Migrating Motor Complex, Cystic Fibrosis, Pancreatic Duct
13 Jun 2017
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Allow entry of digested nutrients but not pathogens. 2 contractions: peristalsis moving food from mouth to anus, segmental contractions mixing and churning , maximizes exposure to digestive enzymes and epithelial. Tonically contracted (minutes to hours: keeps food from moving backwards. Phasic contractions (few seconds: stomach, small intestine. Migrating motor complex sweep slowly down tract 90 mins. Above threshold open voltage gated ca channels action potentials contraction. H+ secreted from apical side, bicarb absorbed into blood. Alkaline tide from stomach measured after a meal. Acinar cells secrete enzymes, epithelial cell linings and secret bicarb solution. Cl- enters via basolaters nkcc transporter leaves via apical cftr channel and cl- re enters via. Crypt cells in small intestine secrete isotonic saline lubricates gut contents. Secreted by exocrine glands, epithelial cell of stomach or small intestine. Linked to apical membrane by protein or lipid stalks. Mucus consists of mucins -- mixture of glycoproteins.
