CHEM237 Lecture Notes - Lecture 9: Alpha And Beta Carbon, Trigonal Planar Molecular Geometry, Beta Turn
1 Jun 2017
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4: quaternary: interactions between multiple subunits/polypeptides: for whatever is synthesized on the ribosome: l aa"s (d aa"s are modified post translationally) This stereoisomer is preferred because of enzymes recognizing one structure and not the other (not to do with stability) 2: side chain collisions restricting conformational space available. Delta carbon- alpha amino bond: aa"s line up every 7 residues so c1 and c8 are stacked on top of each other. 1: parallel orientation: h bonds aren"t straight because n c in the same direction, slightly weaker bonds. Can have a loop that goes over the top or under the bottom (can be straight, helices, domains) Form a barrel structure in the middle and each strand is connected by an alpha helix. 2: antiparallel orientation: n to c in opposite directions so the carbonyl and amide groups point towards each other to crate straight h bonds. Alpha helix, they all point toward the c terminus and allows for a signal.
