CHEM237 Chapter Notes - Chapter 6: Hydrolysis, Radiography, Protein Data Bank

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Peptide bond has two resonance forms and partial double bond character and in a trans configuration. Helical pitch is the distance a helix rises along its axis per turn (n: helical rise per repeating unit (d)=p/n, when right handed, n is positive. Ala is hydrophobic and not really branched, glu and lys are charged so it reacts with water nice: pro, gly, val are unfavourable. Pro causes a kink, and breaks the helix. Glycine too small so it move around too much. Loops are a large group of different, well-defined stuctures that are compact: often involved in protein function. Random coil are non-repetitive, no clear pattern. Fibrous proteins are needed for protective, connective and supportive role: insoluble, generally simpler structures than globular proteins and elongated. A and d amino acid are non-polar which promotes packing. Rich in cysteine residues, which makes the keratin harder. Can be cleaved by reducing agents then reoxidized into a new form (curling your hair)