HLTH 210 Lecture Notes - Lecture 7: Hyaline Cartilage, Bone, Epiphyseal Plate

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Hyperplasia: aka multiplicative growth, the increase in cell number via mitoses, only certain cells in the body can undergo hyperplasia throughout life (ie. blood cells, skin cells, etc) Hypertrophy: aka auxetic growth, the increase in cell size/volume without cell division. Accretionary growth: increase in the amount of extracellular matrix (ie. bone or cartilage) Appositional growth: increase in cell number and increase in ecm at the surface of a tissue. Intersistial growth: increase in cell numbers and increase in ecm throughout the tissue. Bone: is formed by deposition if mineral matrix onto a template (mesenchyme or cartilage) Intramembranous ossi cation: process where bone forms directly from undifferentiated mesenchymal connective tissue, occurs in the at bones of the face, cranial bones and clavicles (not fully ossi ed at birth, allow for compression during expulsion) Osteogenic cells: stem cell provided by the invading blood vessels, and found in the marrow, develops into osteoblasts.

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