HLTH 210 Chapter Notes - Chapter 6.4 & 6.6: Intramembranous Ossification, Hyaline Cartilage, Epiphyseal Plate
19 Feb 2017
School
Department
Course
Professor
Document Summary
Embryonic skeleton consists of hyaline cartilage which is replaced by bone through the process of ossification in utero. Most cartilage is replaced with bone by birth but some cartilage is kept. The process by which compact and spongy bone develop from undifferentiated connective tissue directly. Occurs in cranial and facial bones and the clavicles. Allows skull and shoulders to compress during childbirth. Embryonic mesenchymal cells differentiate and some become osteoblasts. Osteoblasts form a cluster called an ossification centre and produce osteoid (uncalcified matrix) Osteoids calcify over a few days as minerals accumulate and deposit of the matrix, and trap osteoblasts inside during the process. Osteoid secreted near capillaries forms a trabecular matrix, where the blood vessels will eventually become red bone marrow. Process of bone development where bone replaces hyaline cartilage (instead of cartilage becoming bone) Mesenchymal cells differentiate into chondrocytes, producing hyaline cartilage. Osteoblasts form a collar of compact bone around the diaphysis.
