PSYCH261 Lecture Notes - Lecture 13: Intralaminar Nuclei Of Thalamus, Capsaicin, Thalamus
Document Summary
Touch ipsilateral side up to medulla and then contralateral side. Ventral posterior and intralaminar nuclei of the thalamus (relay of sensory information) Touch information goes up to the somatosensory cortex. Conscious experience of touch (how we interpret touch) Main pain receptors (bare nerve endings) respond to chemicals found in heat, etc. C-fibers unmyelinated transmit relatively slowly but brain"s response to the pain is quick duller pain. Thicker fibers sharp pain more likely to have myelin in it. Stronger pain glutamate + substance p (leads to increase intensity of pain) Somatosensory cortex (responds to memory of pain, cues associated with pain) not just about stimulation itself, things associated with pain. Emotional evaluation of pain to structures in the limbic system. Opiates stimulate opiate receptors that reduce the release of substance p in the spinal cord and paraqueductal gray area (relieves pain by inhibiting the release of substance p) effects more centrally.