MICB 201 Lecture Notes - Lecture 6: Metal Resistance, Antimicrobial Resistance, Proteome
Document Summary
All organisms make the same general classes of proteins. All organisms possess the same general classes of genes. Genotype: the particular genes an organism possesses within each class. Phenotype: reflection of the particular proteins an organism makes within each class. Plasmids do not carry genes essential for viability under all environmental conditions. Infection plasmids: have genes encoding proteins granting ability on host to cause an infection: resistance (r) plasmids: have genes encoding proteins granting antibiotic resistance and/or heavy metal resistance to host. Understanding an organism largely means understanding the proteins it can make = its proteome: these da(cid:455)s (cid:373)u(cid:272)h is (cid:272)o(cid:374)(cid:272)luded a(cid:271)out a p(cid:396)oka(cid:396)(cid:455)ote"s p(cid:396)otei(cid:374)s (cid:374)ot (cid:271)(cid:455) stud(cid:455)i(cid:374)g its proteins directly but indirectly by analyzing its genome. Microbiologists (and other biologists) talk about an organism making a particular protein because analysis of its genome suggests it has a gene that seems to encode a similar protein of known function in another organism.
