PCTH 201 Lecture Notes - Lecture 23: Testicular Atrophy, Antidoping, Epitestosterone

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World anti-doping agency (wada: created out of tour de france scandals (late 1990s) From wada official code: (cid:862) to be considered for inclusion on the list of prohibited. Substances and methods, [a substance] needs to meet any two of the following three criteria: be performance enhancing, potentially a health risk, agai(cid:374)st the spirit of sport(cid:863) Catching the cheaters: technology is continually being updated in an effort to test for illegal substances, as technology improves, more ingenious methods of bypassing the resulting tests are created. Brand new compounds/technologies: once uncovered, technology works to adapt, continual cat-and-mouse back-and-forth between the two sides. Enhanced stamina and competitiveness: strychnine, cocaine, ephedrine, amphetamines, caffeine, side effects overstimulation of two major systems: Anabolic steroids: testosterone and analogues e. g. stanozolol, bind to receptors in cell nuclei, stimulate protein production. Enhanced development and/or repair of tissue (i. e. skeletal muscle: numerous adverse effects. But it(cid:859)s all natu al: testosterone : epitestosterone (t:e) ratio.

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