PHAR 454 Lecture Notes - Lecture 12: Prodrug, Hypotension, Aripiprazole
12 Feb 2017
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Document Summary
Abnormalities in frontal lobe, basal ganglia, caudate nucleus, cerebellum, nucleus accumbens and other areas. Adhd = a disorder of executive functioning, which affects: Self-(cid:373)o(cid:374)itori(cid:374)g (cid:894)self a(cid:449)are(cid:374)ess of (cid:449)hat"s goi(cid:374)g o(cid:374) i(cid:374) (cid:455)our (cid:271)od(cid:455)(cid:895) Allergies to food additives/preservatives, hormonal or vestibular system abnormalities, poor parenting, television/video games, diet (sugar, wheat, dairy) Prevalence in children: 8. 7% (2-3 children in a standard 30 child classroom) Mean onset: age ~3 (must have onset by age 12 per dsm5 criteria) Quick and clinically useful rating scale for teachers/parents. Helps capture the patients overall control of their symptoms if ticks are all more on the right side, it is poorly controlled (see last page for case study where this is used) Helpful tool to assess efficacy of treatment trials. Common comorbidities = anxiety, ocd, depressio(cid:374), odd (cid:894)oppositio(cid:374)al defia(cid:374)t disorder(cid:895), tourette"s, autis(cid:373) There"s a higher rate of adhd + ocd + tourette"s (cid:272)o-occurring together.
