PHAR 454 Lecture Notes - Lecture 12: Titration, Cyp2D6, Anticholinergic
6 Apr 2017
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Include non-drug measures and appropriate absorbent products: dis(cid:272)uss (cid:272)halle(cid:374)ges fo(cid:396) t(cid:396)eat(cid:373)e(cid:374)t of ui i(cid:374) the f(cid:396)ail elde(cid:396)ly. Increases with age but ui is normal only in _____ Up to 50% of nursing home residents. Decrease in strength of detrusor muscle may not being getting rid of all the ruine. Decrease in ability to postpone urination external sphincter. Decrease in estrogen in post-menopausal women pelvic floor atrophy. Dm, hf, some cancers, obesity, chronic cough (ex. Urge: overactive bladder (oab) wet = urge urinary incontinence, oab dry (without urinary incontinence) Consider differential diagnoses: uti, cancer, kidney stones etc. More complex cases may require urodynamic testing. Specific type of ui may be determine via history, physical exam. Maintain fluid intake (1. 5-2. 0 l/day); limit after 6 pm. One small rct suggests increase fluids in frail elderly may decrease uui. Bladder training trying to increase bladder capcity. Prompeted voiding go at vertain times of the day to re-train the bladder.
