PHAR 454 Lecture Notes - Lecture 7: Mycoplasma Pneumonia, Haemophilus Influenzae, Gram-Negative Bacteria

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In non-hospitalized, ambulator elderly person, the incidence of acute infections is less than the in children and younger adults. However, the elderly appear to be at increased risk for more sever complications of infection, such as hospitalization or death. Have a 2-5 fold increase in nosocomial infections such as uti, pneumonia, bacteremia and. Infection is the primar cause of death in 1/3 of indiciduals aged 65 years of age and older wound infections. Between 47% and 79% of long term care facility residents in the us, canada and italy have been reported to receive at least 1 course af antibiotics udirng a study period of 1 year. The use of antibiotics was found to be inappropriate 40-50% of the time. Overall, the elderly are more susceptible to serious infections than younger adults. There is a higher morbidity and mortality with infections in the elderly. Extrapulmonary site of infection, delayed resolution, decline in functional status, abnormal gas exchange.

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