PHRM 211 Lecture Notes - Lecture 3: Juvenile Myoclonic Epilepsy, Temporal Lobe Epilepsy, Rolandic Epilepsy

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28 Feb 2020
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Pathophysiology of seizure disorders - epilepsy (part 1) Epilepsy : derives from a greek term epilepsia that we might translate as seizure. Not a disease, but group of disorders characterized by recurrent and usually transient seizures having a sudden onset and spontaneous resolution (not related to fever) Seizure : any interruption of consciousness that might be accompanied by a change in behavior , motor or sensory activity resulting from abnormal electrical discharges in the brain (spells, fits, attacks, convulsions) Brain disorder characterized by enduring predisposition to generate epileptic seizures. By neurobiologic, cognitive, psychological, and social consequences of this condition. Epilepsy is a disorder of the brain defined by any of the following conditions : At least two unprovoked (or reflex) seizures occurring > 24 hrs apart. One unprovoked (or reflex) seizure and a probability of further seizures similar to the general recurrence risk (at least 60%) after two unprovoked seizures, occurring over the next 10 years.

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