BIOL1001 Lecture Notes - Lecture 25: Peptide, C-Terminus, Dehydration Reaction

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9 Aug 2016
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Lecture 25
Amino acids are represented by a single upper case letter
or a three-letter abbreviation.
Valine is known by the letter V or the three-letter symbol
val.
The sequence and the number of amino acids ultimately
determine the protein's shape, size, and function.
Each amino acid is attached to another amino acid by a
covalent bond, known as a peptide bond.
When two amino acids are covalently attached by a
peptide bond, the carboxyl group of one amino acid and
the amino group of the incoming amino acid combine and
release a molecule of water.
Any reaction that combines two monomers in a reaction
that generates H2O as one of the products is known as a
dehydration reaction, so peptide bond formation is an
example of a dehydration reaction.
Peptide bond formation is a dehydration synthesis
reaction.
The carboxyl group of one amino acid is linked to the
amino group of the incoming amino acid.
The resulting chain of amino acids is called a polypeptide
chain.
This end is called the N terminal, or the amino terminal,
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