HLSC 2463U Lecture Notes - Lecture 12: Diuresis, Diabetes Insipidus, C-Peptide
Document Summary
Chronic polydipsia, polyuria, weight loss, polyphagia. Nephrogenic kidney issues, adh is produced but doesn"t fit in the. Pro-insulin inactive form of insulin, needs to be broken down into c. Type 1 deficiency of beta cells. Absorption and nutrient intake from cells is decreased weight loss. At the doctor"s office, blood and urine samples are taken. C peptide is decreased no insulin production or very low levels. Diabetic glucose is thrown out, and stays out, it is an osmotic compound; water follows where glucose is, some water doesn"t come back in. Filtration glucose, sodium, amino acids, and other big particles leave. Glucose pumps are overworked; glucose stays in the tubules; water peptides to form insulin to go into the blood. Insulin binds to receptors and allows glucose to come in. Glucagon increase lipolysis, increase free fatty acids and oxidation, increase ketone bodies. Cells are not getting glucose and therefore are starving.
