HLSC 3473U Lecture Notes - Lecture 17: Insulin Resistance, Impaired Glucose Tolerance, Adipose Tissue
19 Mar 2019
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Document Summary
Islets of langerhans: alpha secrete glucagon, beta secrete insulin. Islets of langerhans receive 10% of the blood supply of the pancreas but only make up 1% of the mass of the pancreas. Maintain fluid balance, filter blood, create hormones that help create rbcs, maintain blood pressure. Diabetes insipidus = tasteless: disorders relating to adh production or adh recognition. 10% of people with t1 have a first degree relative with it. Stress, viruses, and air pollution are said to play a role in the autoimmunity of t1 but more research needs to be done. Degree of obesity, distribution of fat, length of obesity makes a difference. Skeletal muscle and adipose tissue require insulin for glucose transport. Insulin sensitivity body"s biological response to insulin; insulin resistance cells are not responsive to insulin. When insulin reaches the cell it will bind to an enzyme linked receptor on the membrane, tyrosine kinase is the enzyme.
