ANP 1105 Lecture Notes - Lecture 2: Basal Lamina, Tight Junction, Cell Adhesion

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: Frank Feiner

Document Summary

Groups of cells similar structure that perform related function. Sheets that line organs as well as glands made up of epithelium. Upper apical surface exposed to exterior/organ cavity. Must have microvilli; cilia are found in trachea and help get debris from lungs to outside world. Basal surface is lower; includes basal lamina and is adhesive. This is what holds cell to what it is on top of. Acts as a filter, and has a role in movement. Have lateral contacts, ex) tight junctions bind cells together. Supported by connective tissue ---> do not want skin to stay apart; want them to stick --> basement membrane responsible for this. Basement membrane: made up of basal lamina and reticular fibers. Homeostasis: stable internal conditions; even though outside world changing internal conditions the same. Body is constantly adjusting so conditions are stable. Ex of homeostatic imbalance) cancerous epithelial cells don"t respect basement membrane: penetrate/invade underlying tissue.