ANP 1105 Lecture Notes - Lecture 15: Cardiac Output, Stroke Volume, Diastole

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: Joanne Savory

Document Summary

Cardiac output (co) amount of blood pumped by each ventricle in 1 min; co = hr x sv (cardiac output. Maximal co is 4-5 times resting co in nonathletic ppl (20-25l/min: may reach 35 l/min in trained athletes; sv increased from training, cardiac reserve: difference btwn resting and maximal co; athletes can be 7 x co. Regulation of stoke volume sv = edv esv. Edv is affected by duration of ventricular diastole and venous pressure (~120 ml/beat) Esv is affected by arterial blood pressure and force of ventricular contraction (~50 ml/beat: strong contraction = more volume. Normal sv = 120ml/beat (edv) 50ml/beat (esv) = 70ml/beat; which is 60% of blood in its chambers. Three main factors that affect sv: preload: the degree to which cardiac muscle cells are stretched just before they contract (affects. Edv which affects sv); higher preload = higher sv (frank-starling law of the heart)