ANP 1105 Lecture 2: Review 2

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: Jacqueline Carnegie

Document Summary

Membranes are two-dimensional liquid where all lipid and protein molecules di use more or less freely. Permeable to small hydrophobic mol or small polar molecules. Pickets and fences formed by actin-based cytoskeleton. Phospholipids: (75%) phosphatidylcholine (pc) - mainly in er and nuc membrane phosphatidylethanolamine (pe) phosphatidylinositol (pi) phosphatidylserine (ps) - mainly in myelin nerve cells. Flippases: concentrate pe and ps on inner membrane. Glycolipids: (5%) are only found on the outer membrane surface. Provides energy and are markers for cellular recognition. Cholesterol: (20%) increases membrane stability and maintains uidity mainly in plasma membrane and myelin nerve cells cpc. sm. an. co. ma o o o cps. m. pe. Enzymatic activity: an enzyme with its active site exposed to substances in the adjacent solution (part of sequential step of metabolic pathway. Receptor for signal transduction: exposed to outside of cell with binding site for chemical messenger (i. e. hormone). Signal causes conformational change that initiates chain of chemical reactions in the cell.