ANP 1105 Lecture : endocrine system.doc

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Chapter 16: the endocrine system endocrinology- the study of hormones and the endocrine glands. Includes the pituitary gland, thyroid gland, parathyroid gland, adrenal gland, and pineal gland. Chemistry of hormones hormones- chemical substances, secreted by cells into the extracellular fluids, that regulate metabolic function of other cells in the body. Can be classified chemically as either amino acid based or steroids. Long distance chemical signals that travel in blood or lymph throughout the boy. Amino acid based hormones vary from simple amino acid derivatives to peptides to proteins. Steroid hormones are synthesized from cholesterol; only gonadal and adrenocorticol hormones are steroids. Eicosanoids (leukotrienes and prostaglandins) are biologically active lipids made for arachidonic acid and are released by nearly all cell membranes. Leukotrienes are signalling chemicals that mediate inflammation and some allergic reactions. Since the effects of eicosanoids are typically highly localized, they generally act as autocrines and paracrines and do not fit the definition of a true hormone.

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