ANP 1105 Lecture Notes - Lecture 3: Fluid Mosaic Model, Lipid Bilayer, Extracellular Fluid

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: Jacqueline Carnegie

Document Summary

Topic 2: cellular physiology of nerves and muscles. Fluid mosaic model: made of phospholipid bilayer with hydrophilic and hydrophobic lipids (phospholipids). Attached to lipids and proteins on extracellular face. (allows cells to recognize one another) however glycocalyx changes when cell becomes cancerous (it can even avoid recognition by immune system) Function of plasma membrane proteins: transport functions by channels and carriers, enzyme activity, receptors for hormones or neurotransmitters d, cell-cell recognition, attachment to the extra-cellular matrix. Desmosomes: strength and firmness in cells (anchoring junctions) linking of cells to resist mechanical stress. Desmosomes are found in places like epithelial cells, anywhere where there are rubbing actions to pull cells off. Gap junctions: direct communication to cytoplasm between neighbouring cells. Connexions: create channels so that they can have direct communication. E. g walls of uterus where they can act as one system. Tight junctions: stops half digested molecules or digestive enzymes or acids which could end up in your bloodstream.