ANP 1105 Lecture Notes - Lecture 8: Extracellular Fluid, Cell Membrane, Lipid Bilayer

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: William Staines

Document Summary

Topic 2: cellular physiology of nerve and muscle. Membrane: the sac that contains life, it separates the cytoplasm from the external environment. Extracellular space, interstitial fluid (like sea water: very selective of what can pass through the cell membrane, composed of a phospholipid bilayer that selectively and carefully proteins can pass through this barrier. Peripheral proteins: attached to integral proteins, can be enzymes, involved in attachment functions. Cytoskeleton: anchors to pm, can also interact with receptors. Glycocalyx: ensemble of carbohydrates attached to lipids and proteins on extracellular face. Cholesterol: reduces general membrane fluidity and stabilizes its. Receptors for signal transduction: second messengers, found on the outside, binding to a receptor causes a diffusion and an activation, insulin receptors. Tight junctions: fusion of adjacent plasma membranes to prevent passage of molecules. Membrane proteins that fuse, not the membranes. Blood brain barrier: used as a protection mechanism. Desmosomes: molecular linking of cells to resist mechanical stress.