ANP 1105 Lecture Notes - Lecture 11: Erythropoietin, Reticulocyte, Polycythemia Vera

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1- distribution: o2 and nutrients, transportation of metabolic wastes, transport hormones from endocrine organs to target organs. 2- regulation: body temp, distribution, conservation, dissipation, ph in body tissues, plasma proteins, bicarbonate reserve - act as buffers, adequate fluid volume, blood proteins prevent excessive fluid loss from blood stream. 3- protection: platelets, plasma proteins, blood clotting, antibodies, complement, wbcs, prevent infection, foreign invader. Colour is scarlet (o2 rich) to dark red (o2 poor) Male = 5. 6 l female = 4. 5 l. Straw coloured; 90% water and many solutes. Produced in liver (except gamma globulins); functional proteins which remain in blood. Water 90% plasma volume; dissolving and suspending medium for solutes of blood; absorbs heat solutes. Help maintain plasma osmotic pressure and ph levels. Contribute to osmotic pressure and maintain water balance. In blood and tissues: albumin - 60% of plasma proteins. Main contributor to osmotic pressure: globulins - 36% plasma proteins. Transport proteins that bind to lipids, metal ions, fat-soluble vitamins.

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