ANP 1106 Lecture Notes - Lecture 2: Stratum Basale, Air1, Collagen

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1106
• Professor: Jacqueline Carnegie

Document Summary

Epidermal growth factor = hormone that stimulate mitotic activity in the stratum basale. Dead because too far from underlying blood vessels - don"t have nutrients. Amount of melanin and ability to hold on to it will determine skin colour. Sun exposure > encourages melanin production (b/c protective molecule) Melanin absorbs uv and protect the dna from uv light. Rate of melanin production: rate of retention by the neighbouring keratinocytes. Numerous branching processes for transfer of melanosomes to adjacent keratinocytes. Migrate to epidermis from bone marrow; macrophages activate immune system. Have a disc-like sensory nerve ending - touch receptors. Sensory receptors located at the boundary between the epidermis and the dermis. Thick skin: thick: contains all ve of the major layers of the epidermis. Only found on areas that typically experience lots of abrasion (soles of the feet, palms and. Ngertips: thin: contains four layers of the epidermis.