ANP 1106 Lecture 2: Bone

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1106
• Professor: Jackie Carnegie

Document Summary

Bone is a living dynamic tissue which responds to its environment. Reacts to amount of force applied by increasing both the density and amount of roughening on bone or decreasing density when force is reduced or eliminated (paralysis) Bone stores calcium-reabsorbed and transferred to bloodstream when needed. Blood cell formation: where bone marrow is to make blood. Ground substance contains lots of the gags chondroitin sulphate and hyaluronic acid-also chondronectin (adhesive protein) Collagen bres (can have some elastic bres) In damaged areas, perichondrium can form scar tissue because poorly vascularized cartilage repairs badly; ossi cation of cartilage with aging. Chondroblasts: high metabolic rate, immature cartilage cells, actively from cartilage. Chondrocytes: low metabolic rate, mature cartilage cells, maintain cartilage. Lacunae: localized clusters of chondrocytes in cartilage. in clusters because thats where they divided. Location: embryonic skeleton, ends of long bones (epiphyseal plates in growing children), costal cartilages of ribs, cartilages of nose, trachea, pharynx.